Methandriol

Den aktuelle version af siden er endnu ikke blevet gennemgået af erfarne bidragydere og kan afvige væsentligt fra den version , der blev gennemgået den 5. februar 2017; verifikation kræver 1 redigering .

Methandriol
methandriolum
Kemisk forbindelse
Brutto formel	C20H32O2 _ _ _ _ _
Molar masse	304,467
CAS	521-10-8
PubChem	11869527
Forbindelse
Klassifikation
Pharmacol. Gruppe	anabolske steroid
ATX	A14
Farmakokinetik
Metabolisme	lever
Udskillelse	nyrer
Doseringsformer
sublinguale tabletter 10 og 25 mg
Administrationsmetoder
sublingualt
Andre navne
Methylandrostenediol, Anadiol, Androdiol, Anormon, Diandrin, Diolostene, Masdiol, Mestendiol, Metandriol, Metasteron, Methostan, Neosteron, Notandron, Novandrol, Protandren, Stenediol, Stenosteron, Testodiol, Tonormon, Troformone
Mediefiler på Wikimedia Commons

Methandriol er et lægemiddel, der tilhører gruppen af ​​anabolske steroider. Hvidt krystallinsk pulver, lugtfrit. Praktisk talt uopløseligt i vand, opløseligt i alkohol. Med hensyn til kemisk struktur og biologiske egenskaber er det tæt på methyltestosteron, dog har det en lavere androgen aktivitet med en relativt højere anabolsk effekt.

Indikationer for brug

Det bruges til at forbedre proteinanabolisme hos rekonvalescent efter alvorlige skader, operationer, infektionssygdomme og andre sygdomme, osteoporose, væksthæmning, udmattelse osv.

Administrationsvej og doser

De tages sublingualt.Voksne ordineres 0,025-0,05 g om dagen, børn og patienter med væksthæmning - med en hastighed på 1,0-1,5 mg / kg, men ikke mere end 0,05 (50 mg) om dagen. På samme tid udpege fødevarer rig på proteiner. Behandlingsforløbet er 4 uger; pauser mellem forløbene 2-4 uger. Maksimale doser for voksne: enkelt - 0,025 g; dagligt - 0,1 g.

Bivirkninger

Krænkelser af leverfunktion med en stigning i dens størrelse og gulsot, allergiske reaktioner, hos kvinder - viriliseringsfænomener.

Kontraindikationer

Prostatacancer, akut leversygdom. Relative kontraindikationer: graviditet, amning, dekompensation af kulhydratmetabolisme og acidose ved diabetes mellitus. [en]

Noter

1. ↑ Mashkovsky M.D. Lægemidler. - 15. udg., revideret, rettet. og yderligere - M.: "New Wave", 2006. - 1206 s.: ill. ISBN 5-7864-0203-7

Steroidhormoner (eksogene)
Mineralocorticoid receptor modulatorer 11-Dehydrocorticosteron 11-oxokortikosteron 17-deoxycortison 11-Dehydrocorticosteronacetat 11-Deoxycorticosteron deoxycorton deoxycorton deoxycorticosteron Desoxycortone estere 11-Deoxycortisol cortodoxon , cortexolon Cortifen Cortodoxonacetat 11β-Hydroxyprogesteron 16a,18-dihydroxy-11-deoxycorticosteron 17a-Hydroxyaldosteron 18-Hydroxy-11-deoxycorticosteron 19-norprogesteron Aldosteron Kortikosteron Kortikosteronacetat Kortikosteronbenzoat Cortisol (hydrocortison) Benzodrocortison (hydrocortisonbenzoat) Hydrocortamat (hydrocortison diethylaminoacetat) Hydrocortisonestere Kortison Cortisonacetat fludrocortison fludrocorton Fludrocortisonacetat Mometason mometasonfuroat Prednisolon prednazat Prednazolin Prednikarbat prednisolon ethylcarbonatpropionat Prednemustin Prednisolat prednisolon-diethylaminoacetat prednisolonestere Prednison prednisonestere
Glukokortikoid receptor modulatorer Kortisol-lignende og beslægtet (16-usubstitueret) 3α,5α-tetrahydrocorticosteron 5α-dihydrocorticosteron 9a-fluorkortison alfluoron 11-dihydrocorticosteron 11-oxocorticosteron , 17-deoxycortison 11-dehydrocorticosteronacetat 11-deoxycorticosteron deoxycorton , deoxycorton , deoxycorticosteron Desoxycortone estere 11-Deoxycortisol cortodoxon , cortexolon Cortifen Cortodoxonacetat 21-deoxycortisol Δ7-prednisolon Δ7-prednisolon 21-acetat Amebucort Kloroprednison Kloroprednisonacetat Cloprednol Cloprednolacetat Kortikosteron Kortikosteronacetat Kortikosteronbenzoat kortisol hydrocortison benzodrocortison hydrocortisonbenzoat Hydrocortamat hydrocortison diethylaminoacetat Hydrocortisonestere Kortison Cortisonacetat Deprodon Deprodon propionat dichlorizon Dichlorizonacetat Dichlorizondiacetat Difluprednat Endrizon Etiprednol Etiprednol dicloacetat etiprednol dichloracetat fludrocortison fludrocorton Fludrocortisonacetat Fluormetholon Fluormetholonacetat Fluperolon Fluperolonacetat Fluprednisolon Fluprednisolonestere Halopredon Halopredonacetat halopredon diacetat Isoflupredon 9a-fluorprednisolon Isoflupredonacetat Loteprednol Loteprednol etabonat Mazipredon deperzolon Medrison metiprednisolon Methiprednisolonestere præbediolon Prebediolonacetat Prednisolon prednazat Prednazolin Prednikarbat prednisolon ethylcarbonatpropionat Prednimustin Prednisolat prednisolon-diethylaminoacetat prednisolonestere Prednison prednisonestere Pregnenolon pregnenolonacetat pregnenolonsuccinat pregnenolon hemisuccinat Rezocortol Tipredan Tixocortol Butixocort thixocortolbutyrat Buticoscortolpropionat thixocortol pivalat Metazoner og relaterede (16-substituerede) 16a-methyl-11-oxoprednisolon Alclomethason Alclomethasondipropionat Amelomethason beclomethason Beclomethasonestere Betamethason Betamethasonestere Cortobenzen betamethason salicylat Cyclomethason Clobetasol Clobetasol propionat Clobetason Clobetason butyrat Clocortolon Clocortolon estere Cloticason Cloticasonpropionat Cormetason Cormetasonacetat Descinolon Desoxymethason Dexamethason Dexamethasonestere Diflorazon diflorazon diacetat Diflucortolon diflucortolon pivalat Diflucortolon valerat Dimaison Dimeson acetat doxybetazol Fluclorolon flumetason flumetasonacetat flumetason pivalat Fluocinolon Fluocortin Fluokortinbutylat Fluocortolon Fluocortolone estere Flupredniden fluprednileden Fluprednidenacetat Fluticason fluticasonfuroat fluticasonpropionat halokortolon Halomethason Icometason Icometason enbutate Isopredniden Locicortolone Locicortolone dicibat Meclorizon Meclorizon dibutyrat Meprednison methylprednison Meprednisonacetat meprednison hydrogensuccinat methylprednison hemisuccinat Mometason mometasonfuroat Paramethason Paramethasonacetat Paramethason dinatriumphosphat Paramethason fosfat predniliden Predniliden diethylaminoacetat Rimexolon tikabezon Ticabezon propionat Timobezon Timobesonacetat Triamcinolon Triamcinolondiacetat Ulobetasol halobetasol Ulobetasolpropionat Vamorolone Cykliske ketaler (16,17-cykliserede) acrocinonider triamcinolon acroleinid Amcinafal triamcinolonpentanonid Amcinafide triamcinolonacetophenid Amcinonide triamcinolonacetat cyclopentanid Budesonid Cyclesonid Cicortonid Deflazacort azacort Descinolonacetonid Desonid hydroxyprednisolonacetonid Desonid dinatriumphosphat Desonida pivalate Dexbudisonid Drocinonid Drocinonidphosphat Fluazacort Fluclorolonacetonid flucloronid fludroxycortid flurandrenolon , flurandrenolid flumoxonid Flunisolid flunisolidacetat fluocinolonacetonid Cyprocinonid fluocinolonacetonidcyclopropylcarboxylat Fluocinonid fluocinolid , fluocinolonacetonidacetat Procynonid fluocinolonacetonidpropionat Formocortal galcinonid Itrocinonid Rofleponid Rofleponidpalmitat Tralonid Triamcinolonacetonid Flupamezon triamcinolonacetonidmetembonat Triamcinolonacetonidestere Triamcinolon aminobenzal benzamidoisobutyrat TBI-PAB Triclonide
gestogen receptor modulatorer Progesteronderivater Progesteron Queenstron Derivater af retroprogesteron Dydrogesteron Trengeston 17α-hydroxyprogesteronderivater (og nært beslægtede) 17a-hydroxyleret Acetomepregenol mepregenoldiacetat Algeston acetofenid dihydroxyprogesteronacetophenid Anagestone acetat Chlormadinonacetat Chlormethenmadinonacetat Cyproteronacetat Delmadinonacetat flugestone acetat flurogestone acetat flumedoxonacetat Hydroxyprogesteronacetat Hydroxyprogesteron caproat Hydroxyprogesteron heptanoat medroxyprogesteronacetat Megestrolacetat Melengestrolacetat methenmadinonacetat Osateron acetat Pentagestroneacetat proligeston 17a-methyleret Medrogeston Andet haloprogesteron Derivater af 19-norprogesteron 17a-hydroxyleret Gestonorone caproat gestronolhexanoat Nomegestrolacetat norgestomet Segesteronacetat nonsidence , elcometrin 17a-methyleret Demegeston Promegestone Trimegeston Derivater af testosteron Estrany Danazol Dimethisteron Etisteron 19-nortestosteron derivater Estrany Allylestrenol Altrenogest Dienogest Ethinodioldiacetat Linestrenol Norethisteron norethindron Norethisteronacetat Norethisterone enanthate Norethinodrel Norgesterone Norgestrienone Normethandron methylestrenolon Norvinisteron Oxendolone Queenestanolacetat Tibolone Gonans Desogestrel Etonogestrel Gestodene Gestrinon Levonorgestrel Norelgestromin norgestimat norgestrel Spirolactonderivater Drospirenon
Androgen receptor modulatorer Derivater af testosteron Androstenediol dipropionat Boldenone undecylenat Clostebol Clostebol acetat Clostebol caproat Clostebol propionat Cloxotestosteronacetat Prasterone dehydroepiandrosteron , DHEA Prasterone enanthate DHEA enanthate Prasteronsulfat DHEA sulfat quinbolon Testosteron estere testosteron cypionat , testosteron enanthate , testosteron propionat , testosteron undecanoat 17a-alkyleret Bolasteron Calusterone Chlorodehydromethyltestosteron HDMT Fluoxymesteron Formebolon Methandienone methandrostenolon Methandriol methylandrostendiol Methandriol bizenantoylacetat Methandriol dipropionat Methandriolpropionat Methyltestosteron Methyltestosteron 3-hexylether Oxymesteron Penmesterol thiomesteron Derivater af dihydrotestosteron Androstanolone stanolon , dihydrotestosteron , DHT Androstanolone estere Bolazina kapronat Drostanolonpropionat dromostanolonpropionat Epitionostanol Mepitiostan Mesterolone Methenolonacetat Methenolone enanthate Stenbolonacetat 17a-alkyleret Androisoxalone Furazabol mebolazin dimethazin Mestanolone Oxandrolone Oxymethalon Stanozol 19-nortestosteron derivater Bolandiol dipropionat Nandrolon estere nandrolon decanoat , nandrolon phenylpropionat Norklostebol Norclostebolacetat Oxabolone cypionat Trenbolonacetat Trenbolon hexahydrobenzylcarbonat trenbolon cyclohexyl methylcarbonat 17a-alkyleret Etiestrenol Mibolerone Norethandrolone Normethandron methylestrenolon , normetisteron Propetandrol 17α-vinyltestosteronderivater Norvinisteron vinylnortestosteron 17α-ethynyltestosteronderivater Danazol Gestrinon Progestiner ethisteron ( ethinyltestosteron ), levonorgestrel , norgestrel , norethisteron ( norethindron ), linestrenol , norgestrinon Tibolone Progesteronderivater medroxyprogesteronacetat
østrogen receptor modulatorer Estronderivater Estron Estrone estere Estron methylester Estropipat 2-Hydroxyestron 4-Hydroxyestron 4-methoxyestron 8,9-dehydroestron 16a-Hydroxyestron Alestramustine Almestron Atrimustin Clomestron Equilenin Equilin Esterificerede østrogener Estromustine hippulin Hydroxyestron diacetat Østradiolderivater Østradiol østradiol hemihydrat Østradiolestere estradiolacetat , estradiolbenzoat , estradiol cypionate , estradiol enanthate , estradiol undecylat , estradiol valerat Lipoid østradiol Polyestradiolfosfat 2-Hydroxyestradiol 4-Hydroxyestradiol 4-methokiestradiol 7a-methylestradiol 8,9-dehydroestradiol 8β-vinylestradiol 16a-fluorestradiol 16a-iodøstradiol 16a-lactonestradiol 16β,17α-Epiestriol (16β-hydroxy-17α-estradiol) 17a-østradiol alfatraradiol Ethinylestradiol Ethinylestradiol 3-benzoat Ethinylestradiolsulfonat 17a-Epiestriol 16a-hydroxy-17a-østradiol Estriol Østriolestere Polyestriolfosfat 17a-dihydroequilenin 17a-dihydroequilin 17β-dihydroequilenin 17β-dihydroequilin Butolam Cloxestradiol Cloxestradiolacetat konjugerede østrogener Cyclodiol Cyclotriol epiestriol Epimestrol Estetrol Estramustin Estramustin fosfat Estrapronicat Estrazinol østofurat Etamestrol (eptamestrol) Ethinylestriol Ethylestradiol Ethinodiol Ethinodioldiacetat Hexolam Linestrenol Linestrenol phenylpropionat Mestranol Methylestradiol Moxestrol Mitatriendiol Nilestriol Norethisteron Norethinodrel Orestrate Pentolam Prodiam Prolam Promestrin Quinestradiol Quinestrol ERA-63 (ORG-37663) EN-16117